Antibiotics for the treatment of Cholera, Shigella and Cryptosporidiumin children

Table 2 Quality assessment of trials of antibiotics for the treatment of Shigella

Quality Assessment						Summary of Findings
听				Directness		No of events		听
No of studies	Design	Limitations	Consistency	Generalizability to population of interest	Generalizability to intervention of interest	Intervention	Control	Relative Risk (95%CI)
Clinical Failure (Antibiotics): Moderate Outcome Quality
03[25鈥�27]	RCT	No Control or placebo group, so used treatment failure rates	All suggest benefit	All studies were conducted in developing countries	Hospital based	50	听	0.18 (0.1, 0.33) ^b
*Bacteriological Failure (Antibiotics): Low Outcome Quality*
04[25鈥�28]	RCT	No Control or placebo group, so used treatment failure rates	All suggest benefit	All studies except one were conducted in developing countries	Hospital based	09	听	0.04 (0.01, 0.12) ^b

ISSN: 1471-2458