Antibiotics for the treatment of Cholera, Shigella and Cryptosporidiumin children

Table 3 Quality assessment of trials of antibiotics for the treatment of cryptosporidium

Quality Assessment						Summary of Findings
听				Directness		No of events		听
No of studies	Design	Limitations	Consistency	Generalizability to population of interest	Generalizability to intervention of interest	Intervention	Control	Relative Risk (95%CI)
Mortality 鈥� All Cause (Antibiotics vs. Placebo): Low Outcome Quality
02[30, 32]	RCT	One study used nitazoxanide while one used spiramycin	All studies suggested benefit	All studies were conducted in developing country	Hospital based	1	6	0.24 [0.04, 1.45] ^a
*Clinical Failure (Antibiotics vs. Placebo): Moderate Outcome Quality*
02[30, 31]	RCT	听	Both used nitazoxanide and suggested benefit	All studies were conducted in developing country	Hospital based	14	32	0.48 (0.30, 0.75) ^a
*Parasitological Failure (Antibiotics vs. Placebo): Moderate Outcome Quality*
03[30鈥�32]	RCT	Two studies used nitazoxanide While one used spiramycin	All studies suggest benefit	All studies were conducted in developing country	Hospital based	31	51	0.62 [0.46, 0.83] ^a

ISSN: 1471-2458