Table 1 Study characteristics
From: Systematic review of probiotics for the treatment of community-acquired acute diarrhea in children
| 听 | 听 | 听 | Study arms | 听 | 听 | 听 |
|---|---|---|---|---|---|---|
| 听 | 听 | Intervention | 听 | 听 | Control | 听 |
Author | n | Probiotic microorganism (dosage) | Duration & method of treatment | n | 听 | Placebo |
Boudraa [12] | 56 | L. bulgaricus &S. thermophilus (2x108 CFU/g) | 180 mL/kg/day infant formula given after initial oral rehydration | 56 | 听 | Infant formula acidified with lactic acid to match yogurt pH |
Canani [13] | 100 | Lactobacillus GG (6x109 CFU/dose) | 2/day for 5 days in 20 ml water | 92 | 听 | Not described |
| 听 | 91 | S. boulardii (5x109 live organisms/dose) | 2/day for 5 days in 20 ml water | 92 | 听 | 听 |
| 听 | 100 | Bacillus clausii (109 CFU/dose) | 2/day for 5 days in 20 ml water | 92 | 听 | 听 |
| 听 | 97 | L. bulgaricus, L. acidophilus, S. thermophilus, B. bifidum (5x108- 109 CFU/dose) | 2/day for 5 days in 20 ml water | 92 | 听 | 听 |
| 听 | 91 | Enterococcus faecium (7.5x107 CFU/dose) | 2/day for 5 days in 20 ml water | 92 | 听 | 听 |
Cetina-Sauri [18] | 65 | S. boulardii (200 mg/dose) | Every 8 hours in 5ml of cold liquid | 65 | 听 | 200mg glucose in 5ml cold liquid |
Costa-Ribeiro [14] | 61 | Lactobacillus GG (10x109 CFU/day) | 1/day w/oral electrolyte solution | 63 | 听 | Inulin |
Lee [15] | 50 | Lyophilized L. acidophilus and B. infantis (3x109 CFU of each/day) | 1/day for 4 days | 50 | 听 | Not described |
Misra [16] | 105 | Lactobacillus GG (1x109 CFU/dose) | 1/day for 10 days | 105 | 听 | Identical placebo (crystalline microcellulose) |
Rafeey [19] | 40 | L. acidophilus (5x109 CFU/capsule) | 2 capsules/ day | 40 | 听 | Not described |
Veereman-Wauters [17] | Diarrhea duration: 25; Stool frequency: 22 | Lactobacillus GG, L. acidophilus, L. casei, L. plantarum, B. infantis (3x109 CFU/capsule) | 3 capsules/ day for 9 days | 22 | 听 | Identical placebo (maltodextrine) |