Table 2 Effect size estimates of Hib conjugate vaccines on childhood meningitis mortality for inclusion in LiST. (A) Approximated using evidence from existing reviews and can be edited by the LiST user. (B) Estimate of the effectiveness of Hib vaccines against Hib meningitis mortality (risk ratio) from this review. (C) Effect size for Hib conjugate vaccines on meningitis mortality for LiST calculated by multiplying (A) x (B). (D) Uncertainty bounds. 鈥燛ffectiveness of Hib vaccines against Hib meningitis mortality is approximated by incidence of Hib meningitis disease.
| 听 | Proportion of all-cause meningitis mortality due to Hib [1] (A) | Effectiveness of Hib vaccines against Hib meningitis mortality (risk ratio)鈥�(B) | Effect size for Hib vaccine on meningitis mortality (A x B) = (C) | Uncertainty bounds (D) |
|---|---|---|---|---|
African meningitis belt | ||||
1 dose | 0.40 (0.30-0.52) | 0.36 (0.0-0.62) | 0.14 | 0.03-0.20 |
2 doses | 0.40 (0.30-0.52) | 0.91 (0.73-0.97) | 0.36 | 0.27-0.41 |
3 doses | 0.40 (0.30-0.52) | 0.94 (0.78-0.98) | 0.38 | 0.29-0.42 |
Other regions | ||||
1 dose | 0.46 (0.40-0.54) | 0.36 (0.0-0.62) | 0.17 | 0.03-0.22 |
2 doses | 0.46 (0.40-0.54) | 0.91 (0.73-0.97) | 0.42 | 0.34-0.45 |
3 doses | 0.46 (0.40-0.54) | 0.94 (0.78-0.98) | 0.43 | 0.36-0.46 |