Table 1 Demographics and laboratory data of screened patients in the WRHI001 South African Cohort
Variable | Proportion or central measure |
|---|---|
Population demographics and health status | |
Female n (%) | 432 (57%) |
Mean age (sd) | 33.9 (7.7) |
Nationality n (%) | |
鈥僑outh African | 431 (57%) |
鈥僙颈尘产补产飞别补苍 | 287 (38%) |
鈥僌ther African countries | 40 (5%) |
Marital status n (%) | |
鈥僊补谤谤颈别诲 | 174 (24%) |
鈥僁ivorced or separate | 12 (2%) |
鈥侨颈苍驳濒别 | 554 (75%) |
Employed n (%) | 551 (75%) |
Current alcohol use n (%) | 269 (36%) |
Current smoking n (%) | 116 (16%) |
WHO clinical stage | |
鈥僆 | 433 (59%) |
鈥僆滨 | 164 (22%) |
鈥僆滨I | 119 (16%) |
鈥僆痴 | 20 (3%) |
Median CD4 cells/渭L at screening (IQR), n听=听755a | 208 (118-299) |
Median plasma viral load copies/mL (IQR) | 64,782 (17,646鈥�186,662) |
Laboratory screening tests prior to antiretroviral treatment | |
Creatinine clearance n听<听50听mL/min (%) | 4 (1%) |
Microalbumin-to-creatinine ratio mg/mmol n (%) | |
鈥�3.4鈥�33.9 | 40 (5%) |
鈥兲�&驳迟;听34.0 | 2 (0%) |
Urine dipstick n (%) | |
鈥働roteinuria 1+ | 60 (8%) |
鈥働roteinuria 2+ | 14 (2%) |
鈥働roteinuria 3+ | 7 (1%) |
Hepatitis B surface antigen positive n (%) | 60 (8%) |
Abnormal ALT/AST IU/L n (%) in all patients | |
鈥�40鈥�99 (1-2.4 X normal) | 145 (19%) |
鈥�100鈥�199 (2.5-4.9 X normal) | 22 (3%) |
鈥兲墺听200 (鈮�5 X normal) | 4 (1%) |
Abnormal ALT/AST IU/L n (%) If hepatitis B positive | |
鈥�40鈥�99 | 19 (32%) |
鈥�100鈥�199 | 2 (3%) |
鈥兲墺听200 | 2 (3%) |
Anaemia in females n (%) | |
鈥�8鈥�10.0听驳/诲尝 | 40 (9%) |
鈥兲�&濒迟;听8.0听驳/诲尝 | 10 (2%) |
Anaemia in males n (%) | 听 |
鈥�8鈥�10.0听驳/诲尝 | 13 (4%) |
鈥兲�&濒迟;听8.0听驳/诲尝 | 2 (1%) |
Neutrophil count | |
鈥兲�<听0.75听脳听10^9 /L n (%) | 7 (1%) |
鈥僊edian cells (IQR) | 2.2 (1.6-2.9) |
Platelet counts (cells/渭l) n (%) | |
鈥兲�<听50,000 | 3 (0) |
鈥�50,000--125,000 | 25 (3) |