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Table 4 Estimated annual costs (in millions of 2014 US$) of influenza-associated illnesses in Kenya

From: The cost of influenza-associated hospitalizations and outpatient visits in Kenya

Cost Item (per episode)

Hospitalized patients

Outpatients

Best-case scenario

Worst-case scenario

Best-case scenario

Worst-case scenario

Estimated cases

Cost (US$d Millions) (95% CIc)

Estimated cases

Cost (US$d Millions) (95% CIc)

Estimated cases

Cost (US$d Millions) (95% CIc)

Estimated cases

Cost (US$d Millions) (95% CIc)

Children < 5 yearsa

17,875

Ìý

31,115

Ìý

144,322

Ìý

383,977

Ìý

 Total direct costs

Ìý

1.34 (1.10–1.63)

Ìý

2.34 (1.92–2.84)

Ìý

1.25 (1.09–1.41)

Ìý

3.33 (2.89–3.76)

  Facility-based medical costs

Ìý

1.08 (0.89–1.34)

Ìý

1.87 (1.54–2.33)

Ìý

0.62 (0.59–0.66)

Ìý

1.65 (1.56–1.75)

  Transportation costs

Ìý

0.08 (0.06–0.12)

Ìý

0.15 (0.10–0.21)

Ìý

0.07 (0.05–0.09)

Ìý

0.18 (0.13–0.24)

  Other costsb

Ìý

0.20 (0.13–0.27)

Ìý

0.34 (0.23–0.47)

Ìý

0.66 (0.48–0.85)

Ìý

1.76 (1.27–2.25)

 Total indirect

Ìý

0.70 (0.56–0.85)

Ìý

1.21 (0.97–1.48)

Ìý

2.01 (1.23–2.97)

Ìý

5.35 (3.28–7.91)

 Total costs

Ìý

2.04 (1.73–2.41)

Ìý

3.55 (3.01–4.19)

Ìý

3.09 (2.32–4.07)

Ìý

8.23 (6.18–10.84)

Persons ≥5 yearsa

7279

Ìý

14,557

Ìý

156,491

Ìý

946,223

Ìý

 Total direct costs

Ìý

0.55 (0.41–0.69)

Ìý

1.10 (0.81–1.37)

Ìý

0.93 (0.78–1.11)

Ìý

5.64 (4.72–6.69)

  Facility-based medical costs

Ìý

0.41 (0.32–0.53)

Ìý

0.81 (0.63–1.07)

Ìý

0.69 (0.64–0.75)

Ìý

4.20 (3.89–4.55)

  Transportation costs

Ìý

0.05 (0.02–0.09)

Ìý

0.10 (0.04–0.18)

Ìý

0.04 (0.01–0.08)

Ìý

0.24 (0.05–0.50)

  Other costsb

Ìý

0.07 (0.04–0.11)

Ìý

0.15 (0.07–0.22)

Ìý

0.23 (0.10–0.40)

Ìý

1.42 (0.63–2.43)

 Total indirect

Ìý

0.43 (0.26–0.65)

Ìý

0.86 (0.51–1.30)

Ìý

1.69 (1.09–2.40)

Ìý

10.24 (6.61–14.49)

 Total costs

Ìý

1.00 (0.71–1.30)

Ìý

1.99 (1.42–2.59)

Ìý

2.64 (1.99–3.38)

Ìý

15.96 (12.02–20.43)

All ages

25,154

Ìý

45,672

Ìý

300,813

Ìý

1,330,200

Ìý

 Total direct costs

Ìý

1.89 (1.60–2.25)

Ìý

3.44 (2.90–4.09)

Ìý

2.32 (2.08–2.58)

Ìý

10.24 (9.18–11.40)

 Total indirect

Ìý

1.06 (0.86–1.28)

Ìý

1.92 (1.55–2.33)

Ìý

3.87 (2.71–5.24)

Ìý

17.11 (11.98–23.17)

 Total costs

Ìý

2.96 (2.57–3.41)

Ìý

5.37 (4.66–6.19)

Ìý

5.96 (4.80–7.49)

Ìý

26.35 (21.22–33.14)

  1. aEstimated using published rates of influenza-associated disease in Kenya [hospitalization rate (< 5 years = 2.7–4.7 per 1000; ≥5 years = 0.2–0.4 per 1000) and outpatient rate (< 5 years = 13.0–58.0 per 1000; ≥5 years = 4.3–26.0 per 1000)]; bCombines costs for childcare, and healthcare seeking prior and after hospitalization or outpatient visit; cMean cost and 95% confidence intervals estimated using 1000 bootstrap samples
  2. d1 US$ = 90 Kenya Shillings (2014)
  3. Best-case scenario: Assuming the lowest published incidence rate of influenza-associated illness
  4. Worst-case scenario: Assuming the highest published incidence rate of influenza-associated illness