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Table 2 Associations between single BFRs and hyperlipidemia in the NHANES

From: Associations between exposure to brominated flame retardants and hyperlipidemia risk in U.S. Adults

Outcomes

Categorical models

Continuous models

Q1

Q2

Q3

Q4

P trend

OR (95%CI)

P value

PBDE28

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Model 1

1.0 (ref.)

1.42 (1.23, 1.63)

1.69 (1.47, 1.96)

2.31 (1.99, 2.69)

&±ô³Ù; 0.001

1.73 (1.58,1.89)

&±ô³Ù; 0.001

Model 2

1.0 (ref.)

1.12 (0.96, 1.30)

1.15 (0.98, 1.34)

1.28(1.08, 1.52)

0.0058

1.21 (1.09,1.33)

&±ô³Ù; 0.001

PBDE47

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Model 1

1.0 (ref.)

1.25 (1.08, 1.44)

1.33 (1.15, 1.54)

1.69 (1.46, 1.96)

&±ô³Ù; 0.001

1.34 (1.24,1.46)

&±ô³Ù; 0.001

Model 2

1.0 (ref.)

1.10 (0.94, 1.28)

1.09 (0.93, 1.28)

1.24 (1.05, 1.46)

0.0179

1.13 (1.03–1.24)

0.007

PBDE85

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Model 1

1.0 (ref.)

1.13 (0.98, 1.31)

1.32 (1.14, 1.53)

1.50 (1.29, 1.74)

&±ô³Ù; 0.001

1.23 (1.15,1.33)

&±ô³Ù; 0.001

Model 2

1.0 (ref.)

1.07 (0.92, 1.25)

1.11 (0.94, 1.30)

1.18 (1.00, 1.39)

0.0537

1.08 (0.99–1.17)

0.079

PBDE99

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Model 1

1.0 (ref.)

1.17 (1.01, 1.35)

1.26 (1.09, 1.46)

1.47 (1.27, 1.71)

&±ô³Ù; 0.001

1.22 (1.14,1.31)

&±ô³Ù; 0.001

Model 2

1.0 (ref.)

1.10 (0.94, 1.29)

1.04 (0.89, 1.22)

1.19 (1.01, 1.41)

0.0793

1.08 (1.00,1.17)

0.054

PBDE100

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Model 1

1.0 (ref.)

1.35 (1.17, 1.56)

1.33 (1.15, 1.53)

1.66 (1.43, 1.92)

&±ô³Ù; 0.001

1.30 (1.20,1.41)

&±ô³Ù; 0.001

Model 2

1.0 (ref.)

1.18 (1.00, 1.38)

1.15 (0.98, 1.35)

1.30 (1.10, 1.53)

0.0048

1.14 (1.05,1.25)

0.003

PBDE153

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Model 1

1.0 (ref.)

0.92 (0.79, 1.06)

0.99 (0.85, 1.15)

1.11 (0.96, 1.29)

0.106

1.11 (1.03,1.19)

0.009

Model 2

1.0 (ref.)

0.92 (0.79, 1.08)

1.00 (0.85, 1.18)

1.08 (0.91, 1.28)

0.2651

1.06 (0.97–1.16)

0.179

PBDE154

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Model 1

1.0 (ref.)

1.33 (1.15, 1.54)

1.25 (1.08, 1.44)

1.55 (1.33, 1.79)

&±ô³Ù; 0.001

1.25 (1.16,1.35)

&±ô³Ù; 0.001

Model 2

1.0 (ref.)

1.17 (1.00, 1.37)

1.04 (0.88, 1.22)

1.24 (1.05, 1.47)

0.0460

1.10 (1.01,1.20)

0.024

PBDE209

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Model 1

1.0 (ref.)

1.32 (1.14, 1.53)

1.30 (1.12, 1.50)

1.48 (1.28, 1.71)

&±ô³Ù; 0.001

1.39 (1.25,1.54)

&±ô³Ù; 0.001

Model 2

1.0 (ref.)

1.28 (1.10, 1.50)

1.17 (1.00, 1.38)

1.46 (1.24, 1.73)

0.0001

1.37 (1.22,1.54)

&±ô³Ù; 0.001

PBB153

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Model 1

1.0 (ref.)

2.27 (1.97, 2.62)

2.81 (2.43, 3.26)

3.03 (2.61, 3.52)

&±ô³Ù; 0.001

1.50 (1.43,1.58)

&±ô³Ù; 0.001

Model 2

1.0 (ref.)

1.38 (1.16, 1.62)

1.34 (1.10, 1.63)

1.39 (1.13, 1.71)

0.0076

1.12 (1.04,1.20)

0.002

  1. Notes: CI, confidence interval; OR: odds ratio; Q, quartile; Continuous, Ln-transformed concentration of serum BFRs. Model 1 was a crude model without any adjustment. Model 2 was adjusted for age, gender, race, marital status, family income to poverty ratio, BMI, alcohol use and serum cotinine level