Table 1 Characteristics of the study participants according to serum uric acid quartiles by gender
Characteristics | Males | Females | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Q1 | Q2 | Q3 | Q4 | P Value | Q1 | Q2 | Q3 | Q4 | P Value | |
N (participants, %) | 3599 (25.0) | 3599 (25.0) | 3602 (25.0) | 3599 (25.0) | 听 | 3170 (25.0) | 3164 (25.0) | 3173 (25.0) | 3169 (25.0) | 听 |
Age, y | 44 (35, 54) | 42 (34, 51) | 40 (33, 49) | 38 (32, 47) | &濒迟;鈥�0.0001 | 39 (33, 46) | 38 (32, 47) | 39 (32, 48) | 39 (32, 50) | 0.0197 |
Uric acid, 碌 mol/L | 314.4 (287.7, 332.7) | 372.4 (360.1, 384,0) | 420.2 (407.6, 434.0) | 489.1 (465.9, 524.2) | &濒迟;鈥�0.0001 | 221.2 (202.5, 234.0) | 263.7 (254.5, 272.5) | 299.4 (290.0, 309.7) | 353.5 (335.0, 382.5) | &濒迟;鈥�0.0001 |
BMI, kg/m2 | 23.7 (21.8, 25.5) | 24.4 (22.7, 26.2) | 25.1 (23.4, 27.0) | 26.1 (24.2, 28.3) | &濒迟;鈥�0.0001 | 21.1 (19.7, 22.8) | 21.5 (20.0, 23.3) | 21.9 (20.4, 23.9) | 23.1 (21.1, 25.4) | &濒迟;鈥�0.0001 |
Pulse, beats/min | 78 (70, 86) | 78 (71, 86) | 78 (71, 87) | 79 (72, 87) | &濒迟;鈥�0.0001 | 83 (76, 91) | 83 (75, 91) | 83 (75, 92) | 83 (75, 91) | 0.6124 |
SBP, mm Hg | 124 (115, 135) | 124 (116, 135) | 125 (116, 135) | 127 (118, 137) | &濒迟;鈥�0.0001 | 115 (107, 125) | 115 (107, 125) | 116 (107, 126) | 119 (109, 130) | &濒迟;鈥�0.0001 |
DBP, mm Hg | 76 (70, 84) | 77 (71, 84) | 78 (71, 86) | 79 (73, 87) | &濒迟;鈥�0.0001 | 70 (65, 77) | 71 (65, 77) | 71 (65, 78) | 73 (66, 80) | &濒迟;鈥�0.0001 |
FBG, mmol/L | 5.2 (4.9, 5.6) | 5.1 (4.8, 5.5) | 5.2 (4.9, 5.5) | 5.2 (4.9, 5.5) | &濒迟;鈥�0.0001 | 4.9 (4.7, 5.2) | 4.9 (4.7, 5.2) | 5.0 (4.7, 5.3) | 5.0 (4.7, 5.4) | &濒迟;鈥�0.0001 |
Creatinine, 碌 mol/L | 70.2 (64.5, 76.2) | 72.7 (67.1, 78.6) | 73.7 (67.9, 79.9) | 75.6 (69.3, 82.3) | &濒迟;鈥�0.0001 | 49.9 (45.9, 54.1) | 51.9 (47.7, 56.4) | 52.6 (48.3, 57.3) | 54.5 (49.4, 59.8) | &濒迟;鈥�0.0001 |
eGFR, mL/min/1.73m2 | 137.0 (123.7, 152.3) | 132.9 (120.4, 146.4) | 131.7 (118.5, 145.6) | 128.7 (115.7, 143.1) | &濒迟;鈥�0.0001 | 154.4 (139.2, 171.0) | 147.8 (133.3, 164.2) | 144.6 (130.1, 161.2) | 138.8 (123.2, 156.7) | &濒迟;鈥�0.0001 |
TG, mmol/L | 1.2 (0.9, 1.7) | 1.4 (1.0, 1.9) | 1.6 (1.1, 2.2) | 1.9 (1.3, 2.7) | &濒迟;鈥�0.0001 | 0.8 (06, 1.1) | 0.9 (0.7, 1.2) | 1.0 (0.7, 1.3) | 1.2 (0.8, 1.7) | &濒迟;鈥�0.0001 |
TC, mmol/L | 4.8 (4.3, 5.4) | 4.9 (4.4, 5.5) | 5.0 (4.4, 5.5) | 5.1 (4.6, 5.7) | &濒迟;鈥�0.0001 | 4.7 (4.2, 5.2) | 4.7 (4.2, 5.3) | 4.8 (4.3, 5.4) | 5.0 (4.4, 5.6) | &濒迟;鈥�0.0001 |
HDL, mmol/L | 1.2 (1.1, 1.4) | 1.2 (1.0, 1.3) | 1.11(1.0, 1.3) | 1.1 (1.0, 1.2) | &濒迟;鈥�0.0001 | 1.5 (1.3, 1.8) | 1.5 (1.3, 1.7) | 1.4 (1.2, 1.7) | 1.4 (1.2, 1.6) | &濒迟;鈥�0.0001 |
LDL, mmol/L | 2.9 (2.4, 3.4) | 3.0 (2.5, 3.5) | 3.1 (2.6, 3.6) | 3.2 (2.6, 3.7) | &濒迟;鈥�0.0001 | 2.6 (2.1, 3.1) | 2.7 (2.2, 3.2) | 2.8 (2.3, 3.3) | 2.9 (2.4, 3.5) | &濒迟;鈥�0.0001 |
Diabetes, N (%) | 听 | 听 | 听 | 听 | &濒迟;鈥�0.0001 | 听 | 听 | 听 | 听 | 0.0320 |
Yes | 203 (5.6) | 103 (2.9) | 83 (2.3) | 53 (1.5) | 听 | 22 (0.7) | 23 (0.7) | 14 (0.4) | 34 (1.1) | 听 |
No | 3396 (94.4) | 3496 (97.1) | 3519 (97.7) | 3546 (98.5) | 听 | 3148 (99.3) | 3141 (99.3) | 3159 (99.6) | 3135 (98.9) | 听 |
Hypertension, N (%) | 听 | 听 | 听 | 听 | &濒迟;鈥�0.0001 | 听 | 听 | 听 | 听 | &濒迟;鈥�0.0001 |
Yes | 742 (20.6) | 761 (21.1) | 791 (22.0) | 939 (26.1) | 听 | 248 (7.8) | 291 (9.2) | 307 (9.7) | 456 (14.4) | 听 |
No | 2857 (79.4) | 2838 (78.9) | 2811 (78.0) | 2660 (73.9) | 听 | 2922 (92.2) | 2873 (90.8) | 2866 (90.3) | 2713 (85.6) | 听 |
High SBP, N (%) | 听 | 听 | 听 | 听 | &濒迟;鈥�0.0001 | 听 | 听 | 听 | 听 | &濒迟;鈥�0.0001 |
Yes | 554 (15.4) | 552 (15.3) | 569 (15.8) | 682 (19.0) | 听 | 196 (6.2) | 226 (7.1) | 247 (7.8) | 371 (11.7) | 听 |
No | 3045 (84.6) | 3047 (84.7) | 3033 (84.2) | 2917 (81.1) | 听 | 2974 (93.8) | 2938 (92.9) | 2926 (92.2) | 2798 (88.3) | 听 |
High DBP, N (%) | 听 | 听 | 听 | 听 | &濒迟;鈥�0.0001 | 听 | 听 | 听 | 听 | &濒迟;鈥�0.0001 |
Yes | 379 (10.5) | 413 (11.5) | 493 (13.7) | 575 (16.0) | 听 | 111 (3.5) | 112 (3.5) | 123 (3.9) | 187 (5.9) | 听 |
No | 3220 (89.5) | 3186 (88.5) | 3109 (86.3) | 3024 (84.0) | 听 | 3059 (96.5) | 3052 (96.5) | 3050 (96.1) | 2982 (94.1) | 听 |