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Table 2 Risk of bias assessment in the 16 observational studies assessing the association between vaccinations and RA

From: Vaccination and rheumatoid arthritis: an updated systematic review and meta-analysis of data from 25,949,597 participants

Author

Selectiona

Comparabilityb

Outcome

Quality score

ascertainmentc

(Total)

Verstraeten T 2008 [27]

✶✶✶

✶

✶✶

Medium (6)

Bengtsson C 2010 [31]

✶✶

✶✶

✶✶✶

High (7)

Ray P 2011 [23]

✶✶✶✶

✶✶

✶✶✶

High (9)

Chao C 2012 [30]

✶✶✶

✶

✶✶

Medium (6)

Ho TY 2012 [29]

✶✶✶✶

✶✶

✶✶

High (8)

Arnheim-Dahlstrom L 2013 [33]

✶✶✶✶

✶✶

✶✶

High (8)

Angelo MG 2014 [34]

✶✶✶

✶

✶✶

Medium (6)

Persson I 2014 [22]

✶✶✶✶

✶✶

✶✶✶

High (9)

Vaughn DW 2014 [28]

✶✶

✶

✶✶

Low (5)

Lai YC 2015 [21]

✶✶✶

0

✶✶

Low (5)

Bardenheier BH 2016 [32]

✶✶

✶✶

✶✶✶

High (7)

Geier DA 2016 [19]

✶✶✶

0

✶✶✶

Medium (6)

Geng Y 2023 [20]

✶✶✶✶

✶✶

✶✶✶

High (9)

Ju H J 2023 [25]

✶✶✶

✶✶

✶✶

High (7)

Yang G 2023 [26]

✶✶✶

✶✶

✶

Medium (6)

Jung SW 2024 [24]

✶✶✶

✶✶

✶✶✶

High (8)

  1. We assessed the included case-control studies and cohort studies using the relevant items from the NOS scale (Available from: )
  2. a Selection refers to how participants are chosen for the study and whether the selection process is free from bias. b Comparability refers to the extent to which the groups being compared are similar at the baseline, controlling for potential confounding factors. c Outcome ascertainment refers to how the outcomes of interest are measured and whether the measurement process is consistent and reliable