Sexual assault experience, depression, and heavy substance use among German adults: an exploratory mediation analysis

Table 2 Mediation analyses between sexual assault experience (lifetime, childhood event) and depression by sex, adjusted for age, and education (N鈥�=鈥�4,867)

听		听	Lifetime event ^a							听	Childhood event ^b
Depression	听	听	Women			听	Men			听	Women			听	Men
		听	OR	95% BCI		听	OR	95% BCI		听	OR	95% BCI		听	OR	95% BCI
		听	OR	Lower	Upper	听	OR	Lower	Upper	听	OR	Lower	Upper	听	OR	Lower	Upper
Mediator	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听
Hazardous alcohol use	Total effect	听	3.36	2.37	4.60	听	3.59	1.34	7.1	听	5.23	2.80	9.02	听	1.52	0.72	3.86
	Natural direct effect	听	3.36	2.37	4.60	听	3.51	1.31	6.97	听	5.23	2.80	9.02	听	1.31	0.64	2.67
	Natural indirect effect	听	1.00	0.99	1.01	听	1.02	0.98	1.17	听	1.00	1.00	1.00	听	1.16	1.01	2.17
Mediator	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听
Heavy tobacco use	Total effect	听	3.43	2.46	4.76	听	3.60	1.20	7.83	听	5.55	2.86	10.30	听	1.48	0.99	3.46
	Natural direct effect	听	3.38	2.40	4.68	听	3.39	1.12	7.53	听	5.46	2.77	10.16	听	1.22	0.77	2.79
	Natural indirect effect	听	1.02	1.01	1.05	听	1.06	0.99	1.19	听	1.01	0.99	1.07	听	1.21	1.02	1.72
Mediator	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听
Frequent cannabis use	Total effect	听	4.09	2.74	6.79	听	3.62	1.25	7.15	听	7.55	3.19	13.9	听	1.57	1.02	7.07
	Natural direct effect	听	3.31	2.32	4.69	听	3.66	1.26	7.17	听	5.70	3.04	11.06	听	1.57	1.02	7.07
	Natural indirect effect	听	1.23	1.01	1.85	听	1.00	0.95	1.01	听	1.32	0.98	1.91	听	1.00	1.00	1.00

OR, odds ratio; BCI, confidence interval from 1,000 bootstrap samples, ^a Sample size ranged from 2,444 to 2,559 in women and from 2,2232 to 2,299 in men, ^b Sample size ranged from 2,168 to 2,274 in women and from 2,195 to 2,261 in men
Brief description:
There is an association between SAE as a lifetime event and depression among women mediated through heavy tobacco use and frequent cannabis use. In addition, there is an association between SAE as a childhood event and depression among men mediated through hazardous alcohol use and heavy tobacco use

ISSN: 1471-2458