Sexual assault experience, depression, and heavy substance use among German adults: an exploratory mediation analysis

Belau, Matthias Hans; Wiessner, Christian; Sehner, Susanne; Dekker, Arne; Briken, Peer

doi:10.1186/s12889-025-22117-4

Table 3 Mediation analyses between sexual assault experience (lifetime, childhood event) and heavy substance use by sex, adjusted for age, and education (N鈥�=鈥�4,867)

From: Sexual assault experience, depression, and heavy substance use among German adults: an exploratory mediation analysis

听		听	Lifetime event ^a							听	Childhood event ^b
Hazardous alcohol use	听	听	Women			听	Men			听	Women			听	Men
		听	OR	95% BCI		听	OR	95% BCI		听	OR	95% BCI		听	OR	95% BCI
		听	OR	Lower	Upper	听	OR	Lower	Upper	听	OR	Lower	Upper	听	OR	Lower	Upper
Mediator	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听
Depression	Total effect	听	1.79	0.30	5.69	听	5.30	1.60	16.74	听	0.86	0.75	1.29	听	20.44	7.96	72.27
	Natural direct effect	听	1.91	0.30	6.10	听	4.63	1.59	12.58	听	1.00	1.00	1.00	听	19.46	7.47	64.08
	Natural indirect effect	听	0.93	0.86	1.15	听	1.14	0.93	1.72	听	0.86	0.75	1.29	听	1.05	0.99	2.00
Heavy tobacco use	听	听	Women			听	Men			听	Women			听	Men
		听	OR	95% BCI		听	OR	95% BCI		听	OR	95% BCI		听	OR	95% BCI
		听	OR	Lower	Upper	听	OR	Lower	Upper	听	OR	Lower	Upper	听	OR	Lower	Upper
Mediator	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听
Depression	Total effect	听	1.72	1.01	2.65	听	2.67	1.09	5.16	听	2.14	0.83	4.22	听	5.86	2.16	14.86
	Natural direct effect	听	1.55	0.89	2.42	听	2.33	0.99	4.71	听	1.84	0.68	3.84	听	5.61	1.97	14.16
	Natural indirect effect	听	1.10	1.02	1.25	听	1.14	1.01	1.53	听	1.16	0.96	1.51	听	1.04	0.99	1.26
Frequent cannabis use	听	听	Women			听	Men			听	Women			听	Men
		听	OR	95% BCI		听	OR	95% BCI		听	OR	95% BCI		听	OR	95% BCI
		听	OR	Lower	Upper	听	OR	Lower	Upper	听	OR	Lower	Upper	听	OR	Lower	Upper
Mediator	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听	听
Depression	Total effect	听	3.99	1.67	9.92	听	0.46	0.32	1.86	听	3.71	0.53	12.95	听	1.06	0.97	1.71
	Natural direct effect	听	2.74	1.05	7.18	听	0.36	0.24	1.51	听	1.99	0.26	10.50	听	1.00	1.00	1.00
	Natural indirect effect	听	1.45	1.09	2.00	听	1.27	0.94	1.74	听	1.85	0.88	3.07	听	1.06	0.97	1.71

OR, odds ratio; BCI, confidence interval from 1,000 bootstrap samples, ^a Sample size was 2,503 in women and 2,304 in men, ^b Sample size was 2,277 in women and 2,267 in men
Brief description:
There is an association between SAE as a lifetime event and heavy tobacco use mediated through depression among women and men, and between SAE as a lifetime event and frequent cannabis use mediated through depression among women

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ISSN: 1471-2458

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Table 3 Mediation analyses between sexual assault experience (lifetime, childhood event) and heavy substance use by sex, adjusted for age, and education (N鈥�=鈥�4,867)

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