Table 2 Association of trajectories of depressive symptoms, physical activity, and multimorbidity status with rheumatoid arthritis risk
Class | Cases/N (%) | Model 1 HR (95% CI) | Model 2 HR (95% CI) | Model 3 HR (95% CI) |
|---|---|---|---|---|
Depressive symptoms | ||||
鈥僈eep low (class 1) | 668/7221(9.25) | 0.498(0.415鈥�0.598) | 0.581(0.482鈥�0.701) | 0.649(0.533鈥�0.790) |
鈥僊aintain a moderate rating (class 2) | 232/1782(13.02) | 0.699(0.567鈥�0.862) | 0.755(0.611鈥�0.933) | 0.798(0.644鈥�0.988) |
鈥僁ownward trend (class 3) | 140/792(17.68) | 1(Ref.) | 1(Ref.) | 1(Ref.) |
Physical activity | ||||
鈥僐ise rapidly (class 1) | 124/1223(10.14) | 1.396(1.093鈥�1.783) | 1.268(0.992鈥�1.622) | 1.246(0.974鈥�1.595) |
鈥僈eep low (class 2) | 133/1802(7.38) | 1(Ref.) | 1(Ref.) | 1(Ref.) |
鈥僅igh and descending (class 3) | 272/2003(13.58) | 1.971(1.602鈥�2.425) | 1.627(1.315鈥�2.013) | 1.456(1.170鈥�1.812) |
鈥僅igh and rising (class 4) | 392/3558(11.02) | 1.495(1.228鈥�1.819) | 1.296(1.061鈥�1.583) | 1.244(1.016鈥�1.522) |
鈥僁ecline rapidly (class 5) | 119/1209(9.84) | 1.280(1.000鈥�1.639) | 1.183(0.923鈥�1.516) | 1.160(0.905,1.486) |
Multimorbidity status | ||||
鈥僉ow (class 1) | 337/3398(9.92) | 1.141(0.973鈥�1.337) | 1.101(0.937鈥�1.292) | 1.062(0.904鈥�1.248) |
鈥僉owest (class 2) | 278/3335(8.34) | 1(Ref.) | 1(Ref.) | 1(Ref.) |
鈥僅igh (class 3) | 260/1993(13.05) | 1.547(1.306鈥�1.832) | 1.414(1.189鈥�1.682) | 1.305(1.094鈥�1.556) |
鈥僅ighest (class 4) | 165/1069(15.43) | 1.959(1.616鈥�2.376) | 1.627(1.332鈥�1.988) | 1.393(1.131鈥�1.715) |