Fig. 3

Identified time-periods with intensified transmission in any of 14 NYC sewersheds. A shows an example of the measured (dots) and expected wastewater SARS-CoV-2 viral load (blue line = median; darker blue area = 50% CI and lighter blue area = 95% CI), and identified anomalies with SARS-CoV-2 viral load exceeding the expected (red labels). B shows the distribution of all identified anomalies. Asterisks indicate time-periods that exceeded the expected wastewater SARS-CoV-2 viral load with a frequency higher than chance assuming random occurrence per a bootstrapping test (* for P < 0.1 and ** for P < 0.05). Spatial distribution of the anomalies is shown in Fig. S4