Fig. 2
Age distribution and APC-analysis of breast cancer mortality by SDI quintiles, 1992鈥�2021. (A) Temporal change in the relative proportion of breast cancer deaths across 16 age groups, 1992鈥�2021. (B) Age-period-cohort model-derived estimates of local drifts of breast cancer mortality for 16 age groups, 1992鈥�2021. The dots indicate the annual percentage change of breast cancer mortality (% per year), and the shaded areas indicate the corresponding 95% CIs. (C) Age effects are represented by the fitted longitudinal age curves of breast cancer mortality (per 100 000 person-years) and the corresponding 95% CIs. (D) Period effects are represented by the relative risk of mortality of each period compared with the reference (period 2002鈥�2006) adjusted for age and nonlinear cohort effects and the corresponding 95% CI. (E) Cohort effects are represented by the relative risk of mortality of each cohort compared with the reference (cohort 1948鈥�1956) adjusted for age and nonlinear period effects and the corresponding 95% CI. SDI, socio-demographic index; CI, confidence interval