Fig. 3

Association between smoking behavior and incident CVD in the overall population and CKM syndrome subgroups. Multivariable Cox model in the overall population adjusted for age, sex, employment status, income levels, education, physical activity, diet, healthy sleep score, alcohol consumption, body mass index, systolic blood pressure, total cholesterol, diabetes mellitus, the use of antihypertensive and statin/cholesterol lowering medication, and model in subgroups adjusted for age, sex, employment status, income levels, education, physical activity, diet, healthy sleep score, and alcohol consumption. Abbreviations: Ref., reference group for each CVD type; P, P value; CVD, cardiovascular disease; CKM, Cardiovascular-kidney-metabolic; MACE, major adverse cardiovascular events. Note: * indicates statistical significance at α = 0.05; ** indicates statistical significance after Bonferroni correction (α = 0.05/6)