Table 3 Decomposition of the total association between NDVI within 500 m buffer and the risk of total CVD direct and indirect associations mediated by cardiometabolic risk factors
Variable | Associationsa | Proportion mediated, % (95% CI) | |||||
|---|---|---|---|---|---|---|---|
Total | 听 | Indirect | Direct | ||||
HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | ||
Hypertension | 0.86(0.78鈥�0.94) | 0.001 | 1.00(0.99鈥�1.00) | 0.129 | 0.86(0.79鈥�0.94) | 0.001 | 2.52(鈭�0.80,7.91) |
Diabetes mellitus | 0.86(0.79鈥�0.94) | 0.001 | 1.00(0.99鈥�1.00) | 0.020 | 0.86(0.79鈥�0.94) | 0.001 | 2.45(0.33,7.17)* |
Overweight/Obesity | 0.92(0.85鈥�0.99) | 0.036 | 1.00(0.99鈥�1.01) | 0.717 | 0.92(0.85鈥�0.99) | 0.034 | 鈭�1.19(鈭�28.24,9.43) |
BMI continuous | 0.86(0.79鈥�0.94) | 0.001 | 0.99(0.99鈥�1.00) | 0.024 | 0.87(0.79鈥�0.95) | 0.002 | 4.04(0.45,11.95)* |
Dyslipidemia | 0.86(0.79鈥�0.94) | 0.001 | 1.00(0.99鈥�1.00) | 0.302 | 0.86(0.79鈥�0.94) | 0.001 | 1.90(鈭�2.02,7.35) |
TC | 0.86(0.79鈥�0.94) | 0.001 | 1.00(0.99鈥�1.00) | 0.048 | 0.87(0.79鈥�0.95) | 0.001 | 2.75(鈭�0.07,8.46) |
TG | 0.87(0.79鈥�0.95) | 0.003 | 1.00(0.99鈥�1.00) | 0.507 | 0.87(0.80鈥�0.96) | 0.004 | 0.92(鈭�2.33,4.89) |
HDL-C | 0.87(0.79鈥�0.95) | 0.002 | 0.98(0.96鈥�0.99) | 鈥�&濒迟;.001 | 0.89(0.81鈥�0.97) | 0.011 | 16.18(7.37,47.96)* |
LDL-C | 0.86(0.79鈥�0.94) | 0.001 | 1.00(1.00鈥�1.00) | 0.283 | 0.86(0.79鈥�0.94) | 0.001 | 1.02(鈭�0.98,3.98) |
Physical activity | 0.85(0.78鈥�0.93) | 0.001 | 0.99(0.99鈥�1.00) | 0.001 | 0.86(0.79鈥�0.94) | 0.001 | 5.34(2.01,13.55)* |
PM2.5 | 0.85(0.78鈥�0.93) | 0.001 | 0.99(0.99鈥�1.00) | 0.058 | 0.86(0.79鈥�0.94) | 0.001 | 4.16(鈭�0.31,12.05) |
Heatwave days | 0.86(0.78鈥�0.94) | 鈥�&濒迟;.001 | 1.02(1.00鈥�1.04) | 0.017 | 0.84(0.77鈥�0.92) | 鈥�&濒迟;.001 | 鈭�12.82(鈭�48.79,鈭�2.47)* |