Ó£»¨ÊÓƵ

BMI change

 &±ô³Ù;−10%

1,525

57 (3.7)

1.62 (1.24–2.10)

1.89 (1.45–2.46)

1.80 (1.38–2.35)

 <−5% to − 10%

6,197

206 (3.3)

1.43 (1.23–1.65)

1.36 (1.18–1.58)

1.31 (1.13–1.52)

 −5% to + 5%

63,233

1,517 (2.4)

1

1

1

 >+5% to < + 10%

14,103

220 (1.6)

0.68 (0.59–0.79)

0.97 (0.84–1.12)

0.94 (0.82–1.09)

 ≥+10%

5,200

84 (1.6)

0.73 (0.59–0.91)

1.42 (1.13–1.77)

1.35 (1.08–1.69)

BMI group (kg/m²) at the last health screening

 Normal (18.5–23.9)

51,457

985 (1.9)

1

1

 Underweight (< 18.5)

8020

105 (1.3)

0.68 (0.55–0.83)

1.56 (1.28–1.90)

1.57 (1.29–1.91)

 Overweight (24–26.9)

20,545

591 (2.9)

1.51 (1.36–1.67)

0.96 (0.87–1.07)

0.91 (0.82–1.02)

 Obese (≥ 27)

10,236

403 (3.9)

2.06 (1.83–2.31)

1.37 (1.22–1.54)

1.19 (1.06–1.34)

Clinical and demographic characteristics

Age, years

 18–49

43,983

263 (12.6)

1

 ≥50

46,275

1821 (87.4)

6.95 (6.10–7.91)

1.47 (1.14–1.89)

1.38 (1.07–1.78)

Birth cohort

 &±ô³Ù;1940

3201

719 (34.5)

1

1

1

 1940–1949

7276

486 (23.3)

0.29 (0.26–0.32)

0.29 (0.26–0.33)

0.34 (0.30–0.38)

 1950–1959

14,384

354 (17.0)

0.11 (0.09–0.12)

0.11 (0.09–0.12)

0.15 (0.13–0.18)

 1960–1969

29,072

340 (16.3)

0.05 (0.04–0.06)

0.05 (0.05–0.06)

0.10 (0.08–0.11)

 1970–1979

31,187

169 (8.1)

0.02 (0.02–0.03)

0.03 (0.02–0.04)

0.06 (0.05–0.09)

 ≥ 1980

5138

16 (0.8)

0.01 (0.01–0.02)

0.02 (0.01–0.03)

0.04 (0.02–0.07)

Sex

 F±ð³¾²¹±ô±ð

44,394

852 (40.9)

1

 M²¹±ô±ð

45,864

1232 (59.1)

1.41 (1.29–1.54)

1.61 (1.48–1.77)

1.66 (1.49–1.86)

Level of education

 Junior high school or less

10,904

982 (47.1)

1

 Senior high school

38,920

691 (33.2)

0.20 (0.18–0.22)

0.81 (0.72–0.92)

 University or higher

40,434

411 (19.7)

0.11 (0.10–0.13)

0.61 (0.53–0.71)

Marital status

 N±ð±¹±ð°ù married

19,535

128 (6.1)

1

 M²¹°ù°ù¾±±ð»å/³¦´Ç³ó²¹²ú¾±³Ù¾±²Ô²µ

65,266

1554 (74.6)

3.76 (3.14–4.50)

0.87 (0.70–1.08)

 O³Ù³ó±ð°ù^†

5457

402 (19.3)

11.80 (9.67–14.39)

1.22 (0.96–1.55)

Smoking status

 N±ð±¹±ð°ù

65,234

1314 (63.1)

1

 C³Ü°ù°ù±ð²Ô³Ù

20,411

596 (28.6)

1.42 (1.29–1.57)

1.42 (1.27–1.58)

 F´Ç°ù³¾±ð°ù

4613

174 (8.4)

1.91 (1.63–2.23)

1.18 (1.00-1.40)

Alcohol consumption

 N´Ç²Ô±ð/°¿³¦³¦²¹²õ¾±´Ç²Ô²¹±ô

75,324

1574 (75.5)

1

 ≥ 1/·É±ð±ð°ì

13,184

400 (19.2)

1.46 (1.31–1.63)

1.06 (0.94–1.19)

 F´Ç°ù³¾±ð°ù

1750

110 (5.3)

2.99 (2.47–3.63)

1.27 (1.04–1.56)

Fruit and Vegetable intake

 < 3 serves/day

27,745

647 (31.1)

1

 3–4 serves/day

49,734

1122 (53.8)

0.98 (0.89–1.08)

0.91 (0.82-1.00)

 ≥ 5 serves/day

12,779

315 (15.1)

1.09 (0.95–1.24)

0.95 (0.83–1.09)

Baseline LTPA (MET-h/week)

 &±ô³Ù; 1

4758

176 (8.5)

1

 1-7.49

56,069

1063 (51.0)

0.68 (0.58–0.80)

1.02 (0.86–1.20)

 7.5-14.99

13,887

441 (21.2)

1.14 (0.95–1.35)

0.91 (0.76–1.09)

 ≥ 15

15,544

404 (19.4)

0.92 (0.77–1.10)

0.81 (0.68–0.97)

Intensity of occupational PA

 L¾±²µ³ó³Ù

60,828

1326 (63.6)

1

 M´Ç»å±ð°ù²¹³Ù±ð

22,094

492 (23.6)

1.03 (0.93–1.14)

0.88 (0.79–0.98)

‽ö±ð²¹±¹²â

7336

266 (12.8)

1.68 (1.47–1.92)

0.96 (0.84–1.11)

Charlson comorbidity index

 0

17,286

69 (3.3)

1

 1

22,532

95 (4.6)

1.06 (0.78–1.44)

0.88 (0.65–1.20)

 ≥2

50,440

1920 (92.1)

9.57 (7.53–12.17)

3.83 (3.00-4.90)