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Pre-existing chronic conditions

 chronic lung disease

2.41

(1.67, 3.48)

1.64

(1.09, 2.46)

0.017

 sleep apnea

1.42

(1.14, 1.76)

1.17

(0.93, 1.49)

0.186

 a²õ³Ù³ó³¾²¹

1.59

(1.29, 1.95)

1.22

(0.98, 1.52)

0.072

 chronic heart disease

1.17

(0.83, 1.64)

0.88

(0.61, 1.27)

0.502

 d¾±²¹²ú±ð³Ù±ð²õ

1.12

(0.85, 1.46)

0.87

(0.66, 1.17)

0.360

 chronic kidney disease

1.13

(0.71, 1.80)

0.95

(0.55, 1.65)

0.865

 high blood pressure

1.36

(1.16, 1.59)

1.35

(1.13, 1.62)

&±ô³Ù; 0.001

 chronic blood disorder

1.18

(0.59, 2.36)

0.66

(0.30, 1.45)

0.299

 o²õ³Ù±ð´Ç±è´Ç°ù´Ç²õ¾±²õ

1.08

(0.72, 1.62)

0.58

(0.39, 0.87)

0.009

 back problems

1.62

(1.36, 1.93)

1.11

(0.91, 1.36)

0.321

 urinary incontinence

1.33

(0.96, 1.85)

0.91

(0.65, 1.27)

0.563

 bowel disorder

1.71

(1.29, 2.26)

1.06

(0.81, 1.40)

0.658

 weakened immune system

2.35

(1.76, 3.12)

1.46

(1.08, 1.98)

0.015

 chronic neurological disorder

1.73

(1.10, 2.70)

0.94

(0.60, 1.49)

0.801

 chronic fatigue syndrome or fibromyalgia

4.57

(3.00, 6.97)

2.20

(1.39, 3.50)

&±ô³Ù; 0.001

 s³Ù°ù´Ç°ì±ð

1.06

(0.58, 1.94)

0.77

(0.40, 1.50)

0.446

 mental health condition

1.64

(1.39, 1.95)

1.12

(0.93, 1.35)

0.238

 a°ù³Ù³ó°ù¾±³Ù¾±²õ

1.7

(1.44, 2.00)

1.28

(1.04, 1.56)

0.019

Age at infection (ref = 15–34)

-

-

-

-

&±ô³Ù; 0.001

 35–49

1.02

(0.90, 1.16)

1.04

(0.91, 1.19)

0.540

 50–64

1.10

(0.96, 1.26)

0.96

(0.83, 1.12)

0.632

 65+

0.87

(0.74, 1.02)

0.66

(0.54, 0.81)

&±ô³Ù; 0.001

Sex (ref = male)

-

-

-

-

&±ô³Ù; 0.001

 f±ð³¾²¹±ô±ð

1.44

(1.29, 1.60)

1.30

(1.15, 1.46)

&±ô³Ù; 0.001

Ethnicity (ref = white)

-

-

-

-

0.023

 I²Ô»å¾±²µ±ð²Ô´Ç³Ü²õ

1.26

(0.97, 1.64)

1.10

(0.84, 1.46)

0.487

 South Asian

0.97

(0.71, 1.32)

0.94

(0.68, 1.31)

0.715

 East/Southeast Asian

0.64

(0.51, 0.80)

0.63

(0.49, 0.80)

&±ô³Ù; 0.001

 B±ô²¹³¦°ì

0.90

(0.57, 1.44)

0.81

(0.50, 1.31)

0.387

 Arab/West Asian

0.73

(0.48, 1.10)

0.73

(0.47, 1.15)

0.176

 Latin American

0.87

(0.56, 1.34)

0.89

(0.58, 1.38)

0.604

 M¾±³æ±ð»å/°¿³Ù³ó±ð°ù

1.09

(0.80, 1.47)

1.09

(0.79, 1.51)

0.600

Ethno-cultural composition (ref = first quintile)^a

-

-

-

-

0.001

 s±ð³¦´Ç²Ô»å

1.27

(1.07, 1.51)

1.26

(1.05, 1.52)

0.013

 t³ó¾±°ù»å

1.21

(1.03, 1.42)

1.19

(1.00, 1.42)

0.050

 f´Ç³Ü°ù³Ù³ó

1.40

(1.19, 1.64)

1.43

(1.20, 1.70)

&±ô³Ù; 0.001

 fifth (highest)

1.20

(0.99, 1.44)

1.38

(1.12, 1.69)

0.002

 u²Ô°ì²Ô´Ç·É²Ô

1.37

(1.11, 1.70)

1.43

(1.11, 1.84)

0.006

Situational vulnerability (ref = first quintile)^b

-

-

-

-

&±ô³Ù; 0.001

 s±ð³¦´Ç²Ô»å

0.96

(0.82, 1.13)

0.98

(0.82, 1.16)

0.782

 t³ó¾±°ù»å

1.02

(0.87, 1.19)

0.96

(0.81, 1.14)

0.639

 f´Ç³Ü°ù³Ù³ó

1.06

(0.90, 1.25)

0.99

(0.83, 1.18)

0.902

 fifth (highest)

0.78

(0.65, 0.93)

0.68

(0.56, 0.83)

&±ô³Ù; 0.001

 u²Ô°ì²Ô´Ç·É²Ô^c

1.09

(0.89, 1.33)

-

-

-

Pre-existing chronic health symptoms

 f²¹³Ù¾±²µ³Ü±ð

1.98

(1.70, 2.29)

1.22

(1.00, 1.48)

0.047

 loss of appetite

3.08

(1.94, 4.89)

1.82

(1.12, 2.94)

0.016

Number of pre-existing chronic health symptoms (ref = 0)

-

-

-

-

&±ô³Ù; 0.001

 1 or 2

1.29

(1.11, 1.47)

1.21

(1.06, 1.38)

0.005

 3

1.74

(1.43, 2.11)

1.56

(1.26, 1.93)

&±ô³Ù; 0.001

 &²µ³Ù; 3

2.21

(1.92, 2.54)

1.47

(1.20, 1.81)

&±ô³Ù; 0.001

Months since last vaccine dose prior to the month of infection (ref = 3 months or less)

-

-

-

-

&±ô³Ù; 0.001

 not vaccinated

1.96

(1.67, 2.30)

1.54

(1.19, 2.00)

0.001

 4–6 months

1.23

(1.08, 1.40)

1.31

(1.15, 1.50)

&±ô³Ù; 0.001

 > 6 months

1.22

(1.02, 1.46)

1.27

(1.05, 1.52)

0.013

 u²Ô°ì²Ô´Ç·É²Ô

1.11

(0.76, 1.61)

1.01

(0.71, 1.44)

0.960

Time period of first infection (ref = pre-omicron)

-

-

-

-

0.005

 Omicron (December 1, 2021 – date of electronic questionnaire completion)

0.57

(0.50, 0.66)

0.70

(0.55, 0.90)

0.005

 u²Ô°ì²Ô´Ç·É²Ô

1.14

(0.42, 3.11)

1.83

(0.62, 5.36)

0.271

Household member testing positive for SARS-CoV-2 infection (ref = no)

-

-

-

-

&±ô³Ù; 0.001

 y±ð²õ

0.76

(0.68, 0.85)

0.83

(0.74, 0.94)

0.002

 u²Ô°ì²Ô´Ç·É²Ô

1.42

(0.73, 2.77)

1.71

(0.88, 3.34)

0.116