Ó£»¨ÊÓƵ

Pre-existing chronic conditions

 chronic lung disease

0.038

 diagnosed less than 10 years prior to infection

1.94

(1.12, 3.38)

1.54

(0.82, 2.88)

0.181

 diagnosed 10 or more years prior to infection

3.01

(1.82, 4.99)

1.91

(1.08, 3.38)

0.027

sleep apnea

0.196

 diagnosed less than 10 years prior to infection

1.46

(1.16, 1.84)

1.27

(0.98, 1.65)

0.072

 diagnosed 10 or more years prior to infection

1.31

(0.86, 2.00)

1.00

(0.63, 1.58)

0.992

asthma

0.280

 diagnosed less than 10 years prior to infection

1.86

(1.13, 3.05)

1.29

(0.77, 2.16)

0.339

 diagnosed 10 or more years prior to infection

1.56

(1.24, 1.96)

1.17

(0.92, 1.49)

0.196

chronic heart disease

0.305

 diagnosed less than 10 years prior to infection

1.33

(0.84, 2.11)

1.04

(0.62, 1.73)

0.888

 diagnosed 10 or more years prior to infection

0.98

(0.60, 1.60)

0.68

(0.41, 1.12)

0.132

diabetes

0.392

 diagnosed less than 10 years prior to infection

1.24

(0.83, 1.85)

0.98

(0.64, 1.50)

0.920

 diagnosed 10 or more years prior to infection

0.94

(0.65, 1.36)

0.75

(0.50, 1.13)

0.172

chronic kidney disease

0.990

 diagnosed less than 10 years prior to infection

1.25

(0.65, 2.43)

1.06

(0.48, 2.30)

0.893

 diagnosed 10 or more years prior to infection

0.97

(0.50, 1.91)

0.98

(0.40, 2.43)

0.967

high blood pressure

0.007

 diagnosed less than 10 years prior to infection

1.45

(1.16, 1.80)

1.32

(1.05, 1.67)

0.018

 diagnosed 10 or more years prior to infection

1.27

(1.03, 1.57)

1.35

(1.06, 1.71)

0.016

chronic blood disorder

0.416

 diagnosed less than 10 years prior to infection

1.75

(0.57, 5.36)

0.94

(0.26, 3.45)

0.928

 diagnosed 10 or more years prior to infection

0.91

(0.36, 2.33)

0.50

(0.18, 1.41)

0.187

osteoporosis

0.029

 diagnosed less than 10 years prior to infection

1.46

(0.85, 2.50)

0.67

(0.39, 1.15)

0.144

 diagnosed 10 or more years prior to infection

0.81

(0.45, 1.47)

0.48

(0.26, 0.89)

0.021

back problems

0.246

 diagnosed less than 10 years prior to infection

1.37

(1.02, 1.83)

0.99

(0.72, 1.37)

0.951

 diagnosed 10 or more years prior to infection

1.86

(1.50, 2.30)

1.23

(0.96, 1.56)

0.097

urinary incontinence

0.356

 diagnosed less than 10 years prior to infection

1.55

(1.06, 2.26)

1.06

(0.70, 1.60)

0.792

 diagnosed 10 or more years prior to infection

0.94

(0.50, 1.79)

0.61

(0.31, 1.21)

0.157

bowel disorder

-

-

-

 diagnosed less than 10 years prior to infection

1.43

(1.02, 2.00)

Interaction

-

-

 diagnosed 10 or more years prior to infection

2.05

(1.32, 3.16)

Interaction

-

-

weakened immune system

0.037

 diagnosed less than 10 years prior to infection

2.03

(1.37, 2.99)

1.43

(0.93, 2.21)

0.105

 diagnosed 10 or more years prior to infection

2.96

(1.93, 4.55)

1.57

(1.03, 2.38)

0.034

chronic neurological disorder

0.732

 diagnosed less than 10 years prior to infection

1.45

(0.75, 2.81)

0.82

(0.44, 1.49)

0.507

 diagnosed 10 or more years prior to infection

2.02

(1.09, 3.76)

1.16

(0.57, 2.34)

0.689

chronic fatigue syndrome or fibromyalgia

0.020

 diagnosed less than 10 years prior to infection

4.09

(2.28, 7.35)

2.13

(1.10, 4.12)

0.024

 diagnosed 10 or more years prior to infection

5.05

(2.83, 8.98)

1.83

(0.98, 3.42)

0.058

stroke

0.858

 diagnosed less than 10 years prior to infection

0.97

(0.49, 1.94)

0.82

(0.35, 1.91)

0.643

 diagnosed 10 or more years prior to infection

1.32

(0.36, 4.82)

0.81

(0.21, 3.13)

0.763

mental health condition

0.276

 diagnosed less than 10 years prior to infection

1.44

(1.12, 1.86)

1.02

(0.79, 1.33)

0.857

 diagnosed 10 or more years prior to infection

1.90

(1.56, 2.31)

1.20

(0.96, 1.50)

0.109

arthritis

0.156

 diagnosed less than 10 years prior to infection

1.69

(1.32, 2.17)

1.22

(0.91, 1.64)

0.180

 diagnosed 10 or more years prior to infection

1.70

(1.40, 2.08)

1.22

(0.96, 1.55)

0.097

Age at infection (ref = 15–34)

-

-

-

-

&±ô³Ù; 0.001

 35–49

1.02

(0.90, 1.16)

1.04

(0.91, 1.19)

0.568

 50–64

1.10

(0.96, 1.26)

0.94

(0.81, 1.10)

0.429

 65+

0.87

(0.74, 1.02)

0.68

(0.55, 0.83)

&±ô³Ù; 0.001

Sex (ref = male)

-

-

-

-

-

 f±ð³¾²¹±ô±ð

1.44

(1.29, 1.60)

Interaction

-

-

Ethnicity (ref = white)

-

-

-

-

0.016

 I²Ô»å¾±²µ±ð²Ô´Ç³Ü²õ

1.26

(0.97, 1.64)

1.13

(0.85, 1.50)

0.409

 South Asian

0.97

(0.71, 1.32)

0.93

(0.66, 1.30)

0.653

 East/Southeast Asian

0.64

(0.51, 0.80)

0.62

(0.48, 0.79)

&±ô³Ù; 0.001

 B±ô²¹³¦°ì

0.90

(0.57, 1.44)

0.81

(0.50, 1.33)

0.411

 Arab/West Asian

0.73

(0.48, 1.10)

0.72

(0.46, 1.13)

0.152

 Latin American

0.87

(0.56, 1.34)

0.87

(0.57, 1.34)

0.535

 M¾±³æ±ð»å/°¿³Ù³ó±ð°ù

1.09

(0.80, 1.47)

1.10

(0.80, 1.52)

0.554

Ethno-cultural composition (ref = first quintile)^a

-

-

-

-

&±ô³Ù; 0.001

 s±ð³¦´Ç²Ô»å

1.27

(1.07, 1.51)

1.23

(1.02, 1.49)

0.029

 t³ó¾±°ù»å

1.21

(1.03, 1.42)

1.19

(1.00, 1.42)

0.051

 f´Ç³Ü°ù³Ù³ó

1.40

(1.19, 1.64)

1.43

(1.20, 1.71)

&±ô³Ù; 0.001

 fifth (highest)

1.20

(0.99, 1.44)

1.41

(1.15, 1.73)

0.001

 u²Ô°ì²Ô´Ç·É²Ô

1.37

(1.11, 1.70)

1.46

(1.13, 1.88)

0.004

Situational vulnerability (ref = first quintile)^b

-

-

-

-

0.001

 s±ð³¦´Ç²Ô»å

0.96

(0.82, 1.13)

0.98

(0.83, 1.17)

0.825

 t³ó¾±°ù»å

1.02

(0.87, 1.19)

0.95

(0.80, 1.12)

0.51

 f´Ç³Ü°ù³Ù³ó

1.06

(0.90, 1.25)

1.00

(0.84, 1.20)

0.996

 fifth (highest)

0.78

(0.65, 0.93)

0.68

(0.56, 0.83)

&±ô³Ù; 0.001

 u²Ô°ì²Ô´Ç·É²Ô^c

1.09

(0.89, 1.33)

-

-

-

Pre-existing chronic health symptoms

 loss of appetite

3.08

(1.94, 4.89)

1.96

(1.21, 3.17)

0.006

Number of pre-existing chronic health symptoms (ref = 0)

-

-

-

-

&±ô³Ù; 0.001

 1 or 2

1.29

(1.13, 1.47)

1.23

(1.08, 1.41)

0.003

 3

1.74

(1.43, 2.11)

1.68

(1.36, 2.07)

&±ô³Ù; 0.001

 &²µ³Ù; 3

2.21

(1.92, 2.54)

1.66

(1.38, 1.99)

&±ô³Ù; 0.001

Months since last vaccine dose prior to the month of infection (ref = 3 months or less)

-

-

-

-

&±ô³Ù; 0.001

 not vaccinated

1.95

(1.66, 2.29)

1.47

(1.13, 1.93)

0.005

 4–6 months

1.23

(1.08, 1.40)

1.32

(1.16, 1.51)

&±ô³Ù; 0.001

 > 6 months

1.22

(1.02, 1.46)

1.28

(1.06, 1.54)

0.009

 u²Ô°ì²Ô´Ç·É²Ô

1.11

(0.76, 1.61)

1.11

(0.77, 1.62)

0.571

Time period of first infection (ref = pre-omicron)

-

-

-

-

0.007

 Omicron (December 1, 2021 – date of electronic questionnaire completion)

0.57

(0.50, 0.66)

0.67

(0.52, 0.86)

0.002

 u²Ô°ì²Ô´Ç·É²Ô

1.14

(0.42, 3.11)

1.30

(0.04, 47.38)

0.885

Household member testing positive for SARS-CoV-2 infection (ref = no)

-

-

-

-

0.001

 y±ð²õ

0.76

(0.68, 0.85)

0.84

(0.75, 0.95)

0.005

 u²Ô°ì²Ô´Ç·É²Ô

1.42

(0.73, 2.77)

1.79

(0.91, 3.52)

0.094

Interaction between sex and bowel disorder

-

-

-

-

0.043

 Male (ref = no bowel disorder)

-

-

-

-

-

 bowel disorder diagnosed less than 10 years prior to infection

-

-

1.06

(0.60, 1.88)

0.840

 bowel disorder diagnosed 10 or more years prior to infection

-

-

0.55

(0.24, 1.28)

0.166

 Female (ref = no bowel disorder)

-

-

-

-

-

 bowel disorder diagnosed less than 10 years prior to infection

-

-

0.87

(0.55, 1.39)

0.567

 bowel disorder diagnosed 10 or more years prior to infection

-

-

1.78

(1.15, 2.74)

0.009

 Female no bowel disorder (ref = male no bowel disorder)

-

-

1.29

(1.14, 1.45)

&±ô³Ù; 0.001

 Female bowel disorder diagnosed less than 10 years prior to infection (ref = male bowel disorder diagnosed less than 10 years prior to infection)

-

-

1.06

(0.51, 2.18)

0.881

 Female bowel disorder diagnosed 10 or more years prior to infection (ref = male bowel disorder diagnosed 10 or more years prior to infection)

-

-

4.16

(1.62, 10.68)

0.003